Contact us: +27 21 931 7825


About Us

About Us

Founded in 1998, TREAD Research is situated in Tygerberg Hospital, Cape Town, South Africa; and is affiliated with the Division of Cardiology in the Department of Medicine, Faculty of Medicine and Health Science, Stellenbosch University. The organisation is managed by Professor Lesley Burgess and conducts pharmaceutically-sponsored contract clinical research in most medical fields.

In the face of the COVID-19 pandemic, TREAD Research has adapted their safety protocols to protect both staff and trial participants while facing the frontline head-on by becoming involved in both COVID-19 treatment and prevention trials.


TREAD has an outstanding record of award winning recruitment, often over-recruiting by a substantial number. For example for the following studies

Study NameNo. of participants enrolledNo. of participants expectedOver-recruitment
EFC 11570208201040%
The mission of TREAD Research is to protect the rights, welfare and privacy of human subjects who choose to participate in human subject research.

We have undergone successful audits by the American FDA, the SAHPRA, and a number of local and international pharmaceutical research companies and clinical research organisations.

TREAD has experience in a wide range of therapeutic areas, namely: Cardiology & Cardiology Risk Factors, Nephrology, Rheumatology, Osteoarthritis, Gastroenterology, and Vaccines to name a few.

In June 2016, we became the first research organisation in Africa to be awarded accreditation by the Association for the Accreditation of Human Research Protection Programs (AAHRPP) joining an elite group of only 231 research institutions throughout the world to have achieved such accreditation merit.

All research conducted at TREAD Research is reviewed and approved by either a private or university health research ethics committee.

TREAD is committed to advancing responsible research, ethical treatment of human research subjects, and ensuring that the right of every human being to voluntary, informed consent with regards to research is respected. We serve to carry out this mission by:

  • Promoting an environment of respect and understanding of the rights and welfare of human research participants;
  • Ensuring that the risks and benefits of each research study are thoroughly considered; and
  • Ensuring that our human participants are well-informed of their research rights.